NewsFootball TipsMan City Vs Southampton Prediction, Preview, H2H Record, Latest Odds & Betting Angles

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Man City Vs Southampton Prediction, Preview, H2H Record, Latest Odds & Betting Angles

Man City And Southampton Lock Horns In The 2025-26 FA Cup Semi-Final

Wembley | FA Cup SF | Saturday April 25 | 5:15pm

Ahead of Saturday’s FA Cup semi-final, BetVictor News delivers the Man City vs Southampton prediction, preview, H2H record, team news, latest odds, betting tips and more.

Match Odds
25 APR | 16:15
Manchester City
Southampton
Match Betting
Manchester City 1/6
Draw 6/1
Southampton 12/1

Man City Vs Southampton Preview

Throughout the month of April, both sides have beaten Arsenal 2-1 and will now go face-to-face at Wembley with a place in the FA Cup final up for grabs. Unsurprisingly, the Man City vs Southampton odds strongly favour the Cityzens to succeed.

However, the Saints are currently entertaining an exceptional 20-game unbeaten run. The highlight in that spell was the victory over the Gunners in the quarter-final. In the league, Tonda Eckert’s side have propelled themselves into the EFL Championship play-off spots and will be aiming to make their first FA Cup final appearance since 2003.

Interestingly, it’s been exactly 50 years since the Hampshire outfit celebrated their only FA Cup success. But it will take a herculean effort to achieve another victory in 2026. Especially as they have to navigate their way past City – who are looking very ominous.

Premier League betting has installed Pep Guardiola’s side as the title favourites after their wins over the Gunners and Burnley during the week. With the EFL Cup already in the bag, Guardiola will be gunning to add the FA Cup into their already bulging trophy cabinet. A domestic treble is very much the aim for the Spanish boss.

Man City Vs Southampton H2H Record

Since the year 2000, the Man City vs Southampton H2H record has produced one clear winner. City have won 22 of the 36 meetings in all competitions compared to the Saints eight victories. There has been six draws played out since the turn of the century.

Interestingly, the last meeting ended goalless at the back end of the 2024-25 Premier League season. Prior to that, the Cityzens won four of the last five with Soton’s only win coming in a 5th round League Cup clash at St Mary’s – Sekou Mara and Moussa Djenepo scored in a 2-0 win.

Man City Vs Man City H2H record since 2000:

  • Man City wins – 22
  • Draws – 6
  • Southampton wins – 8
Correct Score
25 APR | 16:15
Manchester City
Southampton
Correct Score
Manchester City 3 – 1 8/1
Manchester City 4 – 0 19/2
Manchester City 4 – 1 11/1

Man City Vs Southampton Team News

Centre-backs Josko Gvardiol and Ruben Dias will once again be absent for Man City but Rodri could play some part. The 2024 Ballon d’Or winner was subbed off against Arsenal and missed the midweek victory over Burnley. Nico Gonzalez is an option to fill the void if the Spaniard isn’t passed fit. As is Nico O’Reilly and Bernardo Silva.

As for Southampton, Mads Roerslev and Alex McCarthy will be missing from the matchday squad and doubts surround Jack Stephens availability. He pulled up injured during the warm up against Bristol City during the week.

Man City’s last six in all comps:

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Southampton’s last six in all comps:

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Man City Vs Southampton Predicted Lineups

Man City predicted lineup:

Trafford; Nunes, Khusanov, Guehi, Ait-Nouri; Bernardo, O’Reilly; Savinho, Cherki, Marmoush; Haaland

Southampton predicted lineup:

Peretz; Bree, Harwood-Bellis, Wood, Manning; Downes, Charles; Fellows, Azaz, Scienza; Stewart

Man City Vs Southampton TV Channel, Live Stream And Radio (UK)

Man City vs Southampton is available to watch live in the UK on TNT Sports 1 and BBC One. Live streaming is available via the HBO Max app or a HBO Max sports pass (no contract sign-up required) and BBC iPlayer. Coverage will begin at 4pm (TNT Sports 1) and 4:45pm (BBC One) ahead of an 5:15pm kick-off. For those looking to tune in via radio, talkSPORT and BBC Radio Five Live Sports have you covered.

  • *A valid TV license and TNT Sports subscription is required to watch live in the UK

Man City Vs Southampton Betting Angles

Key Match Stats

  • Man City have reached eight FA Semi-Finals in a row
  • Man City can become the first ever side to contest four consecutive FA Cup finals
  • Southampton haven’t conceded and FA Cup goal this season before half-time

Top Betting Angles for Man City Vs Southampton

Over 4.5 goals: Man City have won 10-1, 2-0, 3-1 and 4-0 to get to the semi-final. Southampton have scored at least two in each of their last seven games. Online at 12/5

Man City win and BTTS: Available at 8/5, which offers potential with Southampton scoring in their last 22 games

Three or more goals: Erling Haaland has failed to score in 14 semi-finals or finals for Man City. However, his luck has to change someday so why not on Saturday? He is 15/2 to bag a hat-trick

FA Cup Winner
16 MAY | 15:30
FA Cup Winner 2025/26
FA Cup Winner 2025/26
Manchester City 2/5
Chelsea 3/1
Leeds 8/1
Southampton 20/1

Man City Vs Southampton Prediction

The FA Cup betting markets for Man City vs Southampton imply their will only be one outcome at Wembley. And it’s extremely hard to back against City re-visiting the Home of Football for the finale next month.

Although, the Saints will arrive in a confident mood with their great league run and superb win over Arsenal in the quarter-final. However, the Cityzens are looking very ominous at the moment and we fancy them to easily navigate their way past a spirited Soton side.

Prediction: Man City 4-1 Southampton (12/1)

If you intend to bet on Man City vs Southampton then please take the time to read through BetVictor’s safe and responsible gambling page which will provide good advice on how to stay in control when betting on football.

Any betting decisions should be made responsibly and there are no guarantees when it comes to match outcomes. All odds correct as of 12pm April 24, 2026.

18+ | gambleaware.org | Please gamble responsibly

Ben Horlock

About the author

After a two-year loan spell with FootItalia, Ben is back in the gaming industry having previously represented Betfair and Entain. He has produced sports content since 2010 when he was a sports journalism student at Southampton Solent University. Whilst on the South Coast, Ben witnessed the Saints rise from League One to the Premier League and lost count of how many goals Rickie Lambert scored along the way. Not only is he a huge football fan, Ben follows a number of sports including tennis, cricket, rugby and F1. He has been published across a number of reputable sites including Sports Illustrated, GiveMeSport, 90Min and ESPN to name but a few. When Ben is not producing content for BetVictor, he can often be found playing tennis or hiking up the Rock of Gibraltar.